Methylcobalamin B-12 with Folic Acid and Intrinsic Factor
PET Factor B-12™ is specifically identified by Epi4Dogs as a widely used oral B-12 option for dogs with exocrine pancreatic insufficiency and insufficient cobalamin levels.
Each easy-to-open capsule combines high-dose methylcobalamin vitamin B-12 with folic acid and intrinsic factor, a formula designed for simple once-daily administration with food.
Epi4Dogs is an independent educational organization and is not affiliated with Wonder Laboratories.
Why Epi4Dogs Recommends PET Factor B-12™
Epi4Dogs reports that approximately 82% of dogs diagnosed with exocrine pancreatic insufficiency have insufficient vitamin B-12 levels. If low B-12 is not corrected, it can interfere with a dog’s ability to respond optimally to an EPI management plan.
When oral B-12 supplementation is selected, Epi4Dogs recommends using a high-dose B-12 product that includes intrinsic factor. Its published guidance specifically identifies Wonder Laboratories PET Factor B-12™ as a widely used option for EPI pets with low B-12.
Epi4Dogs reports successful use supported by individual before-and-after cobalamin blood tests. The organization also explains that these observations are not the same as a controlled clinical trial.
Work with your veterinarian to check cobalamin levels and determine the appropriate supplementation period and maintenance plan for your dog. Epi4Dogs recommends retesting B-12 after the initial supplementation protocol.
Review the complete Epi4Dogs B-12 guidanceWhy B-12 Is Important for Dogs with EPI
Exocrine pancreatic insufficiency, commonly called EPI, occurs when the pancreas does not produce enough digestive enzymes. Without enough enzymes, a dog may have difficulty digesting food and absorbing nutrients.
Dogs with EPI may experience unexplained weight loss, frequent or loose stools, increased appetite, poor coat condition, lethargy or difficulty maintaining normal nutrient levels.
Vitamin B-12 status is an important part of EPI management. PET Factor B-12™ provides oral nutritional support, but it does not replace pancreatic enzymes, diagnostic testing, medication or veterinary care.
More Than Vitamin B-12 Alone
PET Factor B-12™ combines methylcobalamin B-12 with folic acid and intrinsic factor in one convenient daily formula.
Methylcobalamin B-12
1,000 mcg per capsuleVitamin B-12 supports normal red blood cell formation, nervous-system function and cellular energy metabolism.*
Folic Acid
400 mcg per capsuleFolic acid works alongside vitamin B-12 in normal red blood cell formation, cell division and nutrient metabolism.*
Intrinsic Factor
Intrinsic factor is a specialized protein involved in the normal intestinal absorption of vitamin B-12. It is included as part of this three-component oral formula.
B-12 Supports Important Functions Throughout the Body
Daily Feeding Guide
Open the recommended number of capsules and mix the contents into your pet’s food during mealtime once daily.
| Pet Weight | Daily Amount | How to Serve |
|---|---|---|
| Up to 50 lb | 1 Capsule | Open and mix into food once daily |
| 51 lb and over | 2 Capsules | Open and mix into food once daily |
Follow your veterinarian’s instructions when your dog is being treated for EPI or has documented low cobalamin levels.
Choose Your Supply
Supply duration depends on your pet’s weight and daily capsule amount.
| Bottle Size | Pets Up to 50 lb | Pets 51 lb and Over |
|---|---|---|
| 90 Capsules | 90-Day Supply | 45-Day Supply |
| 180 Capsules Best Value | 180-Day Supply | 90-Day Supply |
Supply estimates assume consistent once-daily use according to the product feeding directions.
How to Give PET Factor B-12™
- Select the number of capsules based on your pet’s weight or your veterinarian’s instructions.
- Carefully open each capsule.
- Empty the capsule contents into your pet’s food.
- Mix thoroughly so the powder is evenly distributed.
- Feed once daily during mealtime.
Supplement Facts
as methylcobalamin 1,000 mcg**
Other Ingredients: Gelatin, vegetable cellulose, intrinsic factor and vegetable stearic acid.
Feeding Directions
Empty the contents of the recommended number of capsules into your pet’s food during mealtime once daily. Give one capsule to pets weighing up to 50 pounds and two capsules to pets weighing 51 pounds or more.
Important Veterinary Guidance
Do not feed to dogs under six months of age.
Consult your veterinarian before use if your pet has a diagnosed medical condition, takes medication, has persistent digestive symptoms or is being treated for EPI, pancreatic disease or an intestinal disorder.
Quality You Can Trust
Made in the USA in an FDA-registered facility using Good Manufacturing Practices.
Frequently Asked Questions
Does Epi4Dogs recommend PET Factor B-12™?
Yes. Epi4Dogs specifically identifies Wonder Laboratories PET Factor B-12™ as a widely used oral B-12 option for EPI pets with insufficient cobalamin levels. Its guidance favors high-dose oral B-12 products that include intrinsic factor.
Why do dogs with EPI need B-12 support?
Many dogs with EPI have insufficient B-12 levels. Low B-12 may contribute to poor weight gain, appetite changes, lethargy, loose stools or difficulty responding optimally to an EPI management plan.
Is PET Factor B-12™ clinically proven to treat EPI?
No. Epi4Dogs reports widespread successful use supported by individual before-and-after cobalamin blood tests, but it also explains that these observations have not been established through a controlled clinical trial. The product provides nutritional B-12 support and does not treat the underlying pancreatic enzyme deficiency.
Does this replace pancreatic enzymes?
No. Dogs with EPI generally require pancreatic enzyme replacement and veterinary management. PET Factor B-12™ supplies B-12, folic acid and intrinsic factor as nutritional support.
What form of vitamin B-12 is included?
Each capsule provides 1,000 mcg of vitamin B-12 as methylcobalamin.
What is intrinsic factor?
Intrinsic factor is a specialized protein involved in the normal intestinal absorption of vitamin B-12. Epi4Dogs recommends looking for intrinsic factor when selecting a high-dose oral B-12 product for an EPI dog.
Why is folic acid included?
Folic acid works alongside vitamin B-12 in normal red blood cell formation, cell division and nutrient metabolism.*
How do I give the capsules to my pet?
Open the recommended number of capsules and mix the contents thoroughly into your pet’s food during mealtime once daily.
How many capsules should I give?
The product label recommends one capsule daily for pets weighing up to 50 pounds and two capsules daily for pets weighing 51 pounds or more. Follow your veterinarian’s instructions when using the product for documented low B-12.
Should my dog’s B-12 level be retested?
Dogs with EPI or documented low cobalamin should be monitored by a veterinarian. Blood testing helps determine whether B-12 levels have improved and whether ongoing supplementation is needed.
Can this be given to puppies?
Do not feed this product to dogs under six months of age.
How long will one bottle last?
For pets up to 50 pounds, the 90-count bottle lasts about 90 days and the 180-count bottle lasts about 180 days. For pets weighing 51 pounds or more, they last approximately 45 and 90 days.
*This product is intended to provide nutritional support for animals. It is not intended to diagnose, treat, cure or prevent disease. PET Factor B-12™ does not replace pancreatic enzymes, prescribed medication, diagnostic testing or veterinary care. Consult your veterinarian when your pet has EPI, another medical condition, takes medication or has persistent symptoms.
Epi4Dogs is an independent EPI education and support organization. References to Epi4Dogs are based on its published B-12 guidance. Epi4Dogs is not affiliated with Wonder Laboratories.
Additional Details
- SKU:
- K96882
