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Product Details

Topical Analgesic/Skin Protectant

*Compare to active ingredients of Extra Strength Benadryl® Cream

Diphenhydramine Hydrochloride USP, 2% Extra Strength

Itch Relief Cream contains the most prescribed topical analgesic. It stops the itch at the source by blocking the action of histamine that causes the itch.

It provides local anesthetic action to stop the pain.


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Active IngredientsPurpose

Diphenhydramine hydrochloride, 2%

Topical analgesic

Zinc acetate, 0.1%

Skin protectant
Spacer ImageUses
  • temporarily relieves pain and itching associated with: insect bites, minor burns, sunburn,minor skin irritations, minor cuts, scrapes, rashes due to poison ivy, poison oak and poison sumac
  • dries the oozing and weeping of poison ivy, poison oak and poison sumac
Spacer ImageWarnings:
For external use only
Do not use
  • on large areas of the body, with any other product containing diphenhydramine, even one taken by mouth,on chicken pox or on measles
  • When using this product: avoid contact with the eyes
Spacer ImageDirections
  • adults and children 2 years of age and older, apply to affected area not more than 3 to 4 times daily, or as directed by a doctor
  • children under 2 years of age, consult a doctor.
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Inactive Ingredients: cetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben and purified water.

*This product is not manufactured or distributed by Parke-Davis, owner of the registered trademark Benadryl® Cream.

Made in USA in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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